Active hydrodynamics is a well-documented phenomenon in all sub-Andean basins. Pervasive meteoric water recharge and cross-formational flow cause complexities in the petroleum systems and exploration including biodegradation, remigration, flushing of traps and tilted oil/water contacts (OWCs). The Llanos Basin is an economically important sub-Andean Basin located in central Colombia. The Rubiales/Quifa area is the most extensively developed part of the Llanos Basin and provides a good case study to understand the role of hydrodynamics. This presentation will outline the theory and workflow involved in identifying, mapping and predicting hydrodynamically tilted OWCs and their importance in petroleum exploration and development.